SACN statement on iodine and health
Scientific Advisory Committee on Nutrition (SACN) statement on Iodine and Health http://www.sacn.gov.uk/pdfs/sacn_position_statement_on_iodine_and_healt…
Research, all articles
Age-related and disease-related muscle loss: the effect of diabetes, obesity, and other diseases
The term sarcopenia refers to the loss of muscle mass that occurs with ageing. On the basis of study results showing that muscle mass is only moderately related to functional outcomes, international working groups have proposed that loss of muscle strength or physical function should also...
Low vitamin D status is an independent predictor of increased frailty and all-cause mortality in older men: the Health in Men study
This prospective cohort study in 4203 older men aged 70-88 years in Perth, Western Australia showed an inverse association between plasma 25(OH)D levels and frailty, as well as all-cause mortality, over a period up to 9 years. Context and objective Hypovitaminosis D and frailty are common...
Diet-induced weight loss: the effect of dietary protein on bone
High-protein (>30% of energy from protein or >1.2 g/kg/day) and moderately high-protein (22% to 29% of energy from protein or 1.0 to 1.2 g/kg/day) diets are popular for weight loss, but the effect of dietary protein on bone during weight loss is not well understood. Protein may help...
Dietary antioxidants and primary prevention of age related macular degeneration: systematic review and meta-analysis
Age related macular degeneration (AMD) is the leading cause of severe visual loss in people aged over 50 in the developed world. Early AMD is characterised clinically by yellow deposits known as drusen and changes in pigmentation of the retina. Late AMD develops when there is an ingrowth...
Dietary intakes of choline in US infants, children and women
Background Choline, an essential nutrient, is present in human milk and important for brain function. Adequate intakes (AIs) for choline were established by the IOM in 1998, but nationally representative estimates of intake are limited. Objective To assess intakes and sources of choline in...
Choline in the diets of the US population: NHANES, 2003-3004
Objective To estimate choline intakes of US subpopulations including children, men, women and pregnant women. Background Choline is an essential nutrient which plays critical roles in brain development and homocysteine metabolism. Choline is widely distributed in foods; good sources...
Consumption of one egg per day increases serum lutein and zeaxanthin concentrations in older adults without altering serum lipid and lipoprotein cholesterol concentrations
Lutein and zeaxanthin accumulate in the macular pigment of the retina, and are associated with a reduced incidence of macular degeneration. The objective of the study was to investigate the effect of consuming 1 egg/d for 5-wk on the serum concentrations of lutein, zeaxanthin, lipids and...
Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans
Choline is a required nutrient, and some humans deplete quickly when fed a low-choline diet, whereas others do not. Endogenous choline synthesis can spare some of the dietary requirement and requires one-carbon groups derived from folate metabolism. We examined whether major genetic...
Nutritional importance of choline for brain development
Choline is a dietary component essential for normal function of all cells. In 1998 the National Academy of Sciences, USA, issued a report identifying choline as a required nutrient for humans and recommended daily intake amounts. In ongoing studies we are finding that men have a higher...