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Cholesterol / CVD

Effects of egg ingestion on endothelial function in adults with coronary artery disease: A randomized, controlled, crossover trial


Prevailing recommendations call for restricting intake of dietary cholesterol and eggs for those at risk of heart disease, despite accumulating evidence challenging this association. Our prior studies showed no short-term adverse effects of daily egg intake on cardiac risk factors in at-risk adults.


We conducted this study to determine effects of daily egg consumption in adults with established coronary artery disease (CAD).

Diets Higher in Protein Predict Lower High Blood Pressure Risk in Framingham Offspring Study Adults


Short-term clinical trials suggest that dietary protein lowers blood pressure (BP); however, long-term effects of total, animal, and plant proteins are less clear. Our goal was to evaluate effects of these dietary proteins on mean systolic BP (SBP) and diastolic BP (DBP) and incident high BP (HBP) risk among middle-aged adults in the Framingham Offspring Study.

Dietary cholesterol, heart disease risk and cognitive dissonance

In the 1960s, the thesis that dietary cholesterol contributes to blood cholesterol and heart disease risk was a rational conclusion based on the available science at that time. Fifty years later the research evidence no longer supports this hypothesis yet changing the dietary recommendation to limit dietary cholesterol has been a slow and at times contentious process.

Egg intake and cardiovascular risk factors in adolescents: role of physical activity. The Helena study

Cardiovascular diseases (CVDs) represent the main cause of morbi-mortality in western countries. Serum cholesterol levels have been related to cardiovascular disease (CVD). Egg intake has been indirectly related to the risk of developing CVD because of its high cholesterol content.
The aim of the present study was to examine the association between egg intake and CVD risk factors in adolescents, assessing the possible influence of physical activity.

Effect of dietary cholesterol on plasma cholesterol concentration in subjects following reduced fat, high fibre diet

One hundred and sixty eight subjects participated in a randomised crossover study to determine whether halving or doubling the present dietary cholesterol intake from eggs had any influence on blood cholesterol concentration in people following current dietary recommendations.

Dietary lipids and blood cholesterol: quantitative meta-analysis of metabolic ward studies

To determine the quantitative importance of dietary fatty acids and dietary cholesterol to blood concentrations of total, low density lipoprotein and high density lipoprotein cholesterol.

Meta-analysis of metabolic ward studies of solid food diets in healthy volunteers.

395 dietary experiments (median duration 1 month) among 129 groups of individuals.

A prospective study of egg consumption and risk of cardiovascular disease in men and women

Reduction in egg consumption has been widely recommended to lower blood cholesterol levels and prevent coronary heart disease (CHD). Epidemiology studies on egg consumption and risk of CHD are sparse.

To examine the association between egg consumption and risk of CHD and stroke in men and women.

Design and Setting
Two prospective cohort studies, the Health Professionals Follow-up Study (1986-1994) and the Nurses’ Health Study (1980 — 1994).