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Prenatal folate and other methyl donor intake are currently being evaluated as potential contributors to the development of childhood asthma. Existing studies have been variable, showing both positive and negative associations of dietary methyl donor intake with childhood asthma. This study seeks to look more comprehensively at the dietary intake of methyl donors during pregnancy and its association with the development of childhood asthma.
The term sarcopenia refers to the loss of muscle mass that occurs with ageing. On the basis of study results showing that muscle mass is only moderately related to functional outcomes, international working groups have proposed that loss of muscle strength or physical function should also be included in the definition. Irrespective of how sarcopenia is defined, both low muscle mass and poor muscle strength are clearly highly prevalent and important risk factors for disability and potentially mortality in individuals as they age.
This prospective cohort study in 4203 older men aged 70-88 years in Perth, Western Australia showed an inverse association between plasma 25(OH)D levels and frailty, as well as all-cause mortality, over a period up to 9 years.
Context and objective
Hypovitaminosis D and frailty are common in the older population. We aimed to determine whether 25-hydroxyvitamin D [25(OH)D] concentrations are associated with frailty and mortality.
High-protein (>30% of energy from protein or >1.2 g/kg/day) and moderately high-protein (22% to 29% of energy from protein or 1.0 to 1.2 g/kg/day) diets are popular for weight loss, but the effect of dietary protein on bone during weight loss is not well understood. Protein may help preserve bone mass during weight loss by stimulating insulin-like growth factor 1, a potent bone anabolism stimulator, and increasing intestinal calcium absorption. Protein-induced acidity is considered to have minimal effect on bone resorption in adults with normal kidney function.
Choline, an essential nutrient, is present in human milk and important for brain function. Adequate intakes (AIs) for choline were established by the IOM in 1998, but nationally representative estimates of intake are limited.
To assess intakes and sources of choline in diets of US non-breastfed infants, children 1-12 yrs and women 18-45 yrs, using NHANES 1999-2004 data.