The term sarcopenia refers to the loss of muscle mass that occurs with ageing. On the basis of study results showing that muscle mass is only moderately related to functional outcomes, international working groups have proposed that loss of muscle strength or physical function should also...
In the 1960s, the thesis that dietary cholesterol contributes to blood cholesterol and heart disease risk was a rational conclusion based on the available science at that time. Fifty years later the research evidence no longer supports this hypothesis yet changing the dietary...
This prospective cohort study in 4203 older men aged 70-88 years in Perth, Western Australia showed an inverse association between plasma 25(OH)D levels and frailty, as well as all-cause mortality, over a period up to 9 years. Context and objective Hypovitaminosis D and frailty are common...
High-protein (>30% of energy from protein or >1.2 g/kg/day) and moderately high-protein (22% to 29% of energy from protein or 1.0 to 1.2 g/kg/day) diets are popular for weight loss, but the effect of dietary protein on bone during weight loss is not well understood. Protein may help...
Background: Dietary protein intake may help to manage blood pressure (BP) and prevent complications associated with elevated BP. Objective: The objective of this study was to determine whether 4 wk of increased protein intake (∼25% compared with ∼15% of energy intake that isoenergetically...
Purpose Advice about the role of eggs in the diet has changed several times over the decades. The aim of the current paper is to evaluate published evidence reporting associations between egg consumption, egg nutrients and health. Design/methodology/approach The scientific literature was...
Objective To estimate choline intakes of US subpopulations including children, men, women and pregnant women. Background Choline is an essential nutrient which plays critical roles in brain development and homocysteine metabolism. Choline is widely distributed in foods; good sources...
Quantitative relations between dietary fat and cholesterol and plasma lipid concentrations have been the subject of much study and controversy during the past 40 years. Previous meta-analyses have focused on the most tightly controlled, highest-quality experiments. To test whether the...
Highlights Brain orexin/hypocretin cells are stimulated by dietary amino acids (AAs) AA sensing involves K-ATP channels and system-A transporters Nonessential AAs stimulate orexin/hypocretin cells more than essential AAs AA presence prevents glucose from blocking orexin/hypocretin cells...